Neurological Recordings with Graphene

THE NEUROGRAPHENE PROJECT focuses on the fabrication of a graphene-based multielectrode array (MEA) prototype for local stimulation and recording of brain activity. It is our hypothesis that characteristics of graphene such as flexibility, high biocompatibility and conductivity can be exploited into engineering an optimal brain interface. While the optimization of implanted MEAs is still a challenge in the neuroscience/surgical fields, the properties of graphene suggest that it could overcome problems that the materials currently used have, while providing additional benefits. The devices that we propose here have the advantages of being formed by a large number of microelectrodes arrayed on flexible substrates with small geometrical size, will adapt well to the brain, induce minimum reactions, and provide recordings with high signal to noise ratio.

THE OBJECTIVES of this project are to validate graphene as a brain interface material, to develop devices for both recording neural activity and for brain stimulation, to test these expected advantages/properties in the brain of experimental animals, and to take the first steps towards approval for use in humans. To achive the objectives of the project, a multidisciplinary consortium that covers the most important research areas has been formed, including technological, biological/medical and the industrial aspects.

SUCCESS OF NEUROGRAPHENE will have an impact at a number of levels:

  1. Technological impact that could reveal graphene as the brain interface of the future
  2. Impact on basic neuroscience research, with better interfacing that could be expanded to other formats and applications. Currently, the study of the brain is a main scientific challenge heavily dependent on technological developments
  3. Clinical neurological impact due to the intrinsically compatibility of graphene with imaging techniques (such as magnetic resonance).

GRAPHENE MEA PROTOTYPES fabricated in NEUROGRAPHENE project will facilitate the further industrial uptake by a European company partner in this project and the commercialization of innovative bio-interfacing measurements tools. Our neuroprosthetic prototypes will also provide new outputs to the global Flagship, complementing the overall project and promoting the envisaged successful Graphene Flagship project realisation.